Analytical Testing

  • –>NITROGEN CONTENT
    Substitution of amine resins and loaded resins
  • LOSS ON DRYING
    Amount of residual solvent in resin
  • FTIR
    Confirms Identity
  • PARTICLE SIZE
    Measures size of bead
  • MESH SIZE
    Bead size range and uniformity of beads
  • SWOLLEN VOLUME
    Swelling of the resin in DCM solvent
  • DIPEPTIDE CONTENT
    Test for dipeptide side products on loaded resins that may form in manufacture
  • CROSSLINKING
    The level of linking between polymer chains. Relates to resin swelling
  • KAISER TEST
    Test for unprotected Amine groups on resin

Optional Tests may attract an additional charge

  • ELEMENT ANALYSIS
    Measures substitution
  • FmPip
    Spectroscopic substitution measurement

Amino Acids & Derivatives

  • MOLECULAR FORMULA
    Empirical identity marker
  • MOLECULAR WEIGHT
    Empirical identity marker
  • FTIR
    Confirms identity
  • MELTING POINT
    Indicates identity and purity
  • OPTICAL ROTATION
    Indicates identity and purity
  • SOLUBILITY
    Test for insoluble impurities, inorganic salts
  • NMR
    Confirms identity
  • TLC
    Test of purity
  • HPLC
    Test of purity
  • NITROGEN ASSAY
    Test of purity
  • RESIDUAL SOLVENTS
    Residual solvents from manufacture. Purification by 1H NMR integration
  • LOSS ON DRYING
    Test for residual volatile solvents
  • WATER CONTENT
    Test hydrate form and residual water content

Optional Tests may attract an additional charge

  • OPTICAL PURITY
    Measures amount of opposite enantiomer
  • KAISER TEST FOR FREE AMINO ACIDS
    Test for unprotected amino acid impurities
  • ELEMENTAL ANALYSIS
    Confirms molecular formula and purity

Peptides

  • MOLECULAR FORMULA
    Empirical identity marker
  • MOLECULAR WEIGHT
    Empirical identity marker
  • SEQUENCE
    Report of amino acid order
  • HPLC
    Test purity
  • MASS SPEC
    Confirms identity

Optional Tests may attract an additional charge

  • ENDOTOXIN
    Level of pyrogenic substances
  • AMINO ACID ANALYSIS
    Confirms identity
  • AMINO ACID CONTENT
    Identifies amino acid
  • AMINO ACID SEQUENCE
    Denotes order of amino acids
  • PEPTIDE CONTENT
    Determines quanity of peptide in sample
  • CE
    Test purity
  • WATER CONTENT
    Indicates in part peptide content – mg of actual peptide in mg of product
  • ELLMAN’S TEST
    Test for uncyclized cysteine side chains
  • NMR
    Confirms identity
  • pH/pl Measurement
    Confirms electronic state
  • Melting Point
    Indicates identity and purity