Rink Amide-MBHA Resin (Knorr Resin)
This resin is less acid sensitive than Rink Amide resin because the benzhydrylamine linker is joined to the support through an electron-withdrawing acetamido spacer . Normally the product is detached from the resin using 95% TFA in DCM plus scavengers as required by the composition of the substrate [1, 2]. However, it is also useful for preparing peptides. Boussard, Cyrille et al. has recently reported that. Synthesis of tri- and tetra- and pentapeptides were performed via a solid phase synthesis methodology using a Rink Amide MBHA resin .
 Bernatowicz, M. S., Daniel, S. B., Koster, H., Tetrahedron Lett., 1989, 30, 4645
 M. Lebl, et al., J. Comb. Chem., 1999, 1, 474
 Boussard, Cyrille, et al., European Journal of Medicinal Chemistry, 2002, 37(11), pp, 883-890
- 100-200 mesh
- 0.5-1.1 mmol/g
- 1% DVB